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​​​​​Risk Factors for Specific Pa​thogens​

MDR Pathogens
(i.e. Pseudomonas)
MRSA
Fungal
MDR Pathogens
Recent broad spectrum antibiotics within 90 days
MRSA
MRSA nares positive/colonized
Fungal
Recent broad spectrum antibiotics within 90 days
MDR Pathogens
Recent hospitalization >2 days within 90 days
MRSA
Chronic dialysis within 30 days
Fungal
Hematologic malignancy or Chemotherapy
MDR Pathogens
Residence in Long-Term Care Facility
MRSA
Recent invasive surgical procedure
Fungal
Parenteral nutrition
MDR Pathogens
Family member with MDR infection
MRSA
Injectable drug users
Fungal
Renal replacement therapy in ICU
MDR Pathogens
Current hospitalization of ≥ 5 days
MRSA
Presence of a purulent skin infection
Fungal
Prolonged neutropenia (>7 days)
MDR Pathogens
Mechanical ventilation ≥ 5 days
MRSA
Implantable prosthetic devices
Fungal
Recent abdominal surgery or suspicion of perforated bowel
MDR Pathogens
Immunosuppressive disease or therapy
MRSA
Immunosuppressive disease or therapy
Fungal
Immunosuppressive disease or therapy
MDR Pathogens
Structural lung disease (i.e. COPD)
MRSA
Presence of a central venous catheter
Fungal
Implantable prosthetic devices

Empiric Drugs of Choice

MDR Pathogens
Cefepime or Piperacillin/ Tazobactam
MRSA
Vancomycin
Fungal
Micafungin ​​​​
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